The Effects of Dentifrice Mixed with Potassium Nitrate, Cetylpyridinium Chloride and Zea Mays L. Extractin Preventing Dentin Hypersensitivity and Gum Diseases
황경숙, 이선경, 김성훈, 황지현, 권하정, Chae Sang-Kyun, 성영은, 김찬호, 이존환, 박용덕,
소속 상세정보
황경숙 ( Hwang Kyung-Sook ) - Shinheung College Department of Dental Technology
이선경 ( Lee Sun-Kyoung ) - Kyung Hee University School of Dentistry Department of Preventive and Social Dentistry and Institute of Oral Biology
김성훈 ( Kim Seong-Hoon ) - Kyung Hee University School of Dentistry Department of Preventive and Social Dentistry and Institute of Oral Biology
황지현 ( Hwang Jee-hyun ) - Kyung Hee University School of Dentistry Department of Preventive and Social Dentistry and Institute of Oral Biology
권하정 ( Kwon Ha-Jeong ) - Kyung Hee University School of Dentistry Department of Preventive and Social Dentistry and Institute of Oral Biology
( Chae Sang-Kyun ) - Amorepacific Corporation R&D Center
성영은 ( Sung Young-Eun ) - Amorepacific Corporation R&D Center
김찬호 ( Kim Chan-Ho ) - Amorepacific Corporation R&D Center
이존환 ( Lee John-Hwan ) - Amorepacific Corporation R&D Center
박용덕 ( Park Yong-Duk ) - Kyung Hee University School of Dentistry Department of Preventive and Social Dentistry and Institute of Oral Biology
KMID : 1157520120080010057
Abstract
Objective: The purpose of this clinical study was to test the efficacy and safety of dentifrice which has effects of reducing dental hypersensitivity (sodium mono fluordie phosphate), anti bacterial and anti immflamatory effects.
Methods: 91 Korean adult subjects have participated and scaling was given right before the initial oral examination to set the oral condition same amongst the subjects. After the run-in period over two weeks, subjects brushed only with distributed dentifrice for three month of time period. The final data sets from dentifrice B and dentifrice C were compared to the control group to compare the improvements using mixtures with sodium mono fluoride phosphate, cetylpyridium chloride, and Zea mays L. unsaponifiable extraction in different concentration.
Results: Over three months period, both test group 1(B) and test group 2(C) each showed 34.98% and 27.95% improvements in reduction of dentin hypersensitivity. Both test group 1(B) and test group 2(B) showed 39.22% and 31.5% statistically significant improvements in plaque index (p<0.05). Test group 1(B) and test group 2(C) each showed 21.15% and 30.95% improvements in gingival index (p<0.05).
Conclusion: The ingredients of sodium mono-fluoride phosphate to strengthen enamel, KNO3 to reduce dentin hypersensitivity, CPC and Zea Mays L. unsaponifiable extraction to prevent gingivitis were indeed effective in protecting sensitive gingiva. No side effects were found throughout the whole body including the oral cavity of the subjects.
키워드
dentifrice; hypersensitivity; potassium nitrate; Zea Mays L.
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